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High-Intensity NIPPV for Acute COPD Exacerbations?
NIPPV is frequently used in the management of critically ill patients presenting with an acute COPD exacerbation, as NIPPV decreases the rates of intubation...
Naloxone for OHCA?
The incidence of opioid-associated out-of-hospital cardiac arrests continues to rise. Current guidelines for the resuscitation of patients with OHCA advise the clinician to consider...
Continuous or Intermittent B-Lactam Infusions for Sepsis?
Timely administration of broad-spectrum antibiotics is a critical pillar in the resuscitation of patients with sepsis. B-lactam antibiotics are an important class of antibiotics...
What Oxygenation Strategy Should We Use for COVID-19 Patients?
Patients with COVID-19 can require supplemental oxygen for acute hypoxemic respiratory failure. While international guidelines recommend a target SpO2 between 90-96%, a safe oxygenation...
Should We Use NIPPV for Preoxygenation for All Intubations?
Over 1 million critically ill patients are intubated each year in the US. Hypoxemia occurs in up to 20% of patients and can lead...
Cefepime vs. Piperacillin-Tazobactam for Infection? The ACORN Trial
Timely and appropriate administration of empiric broad-spectrum antibiotics for adult patients with sepsis is critical. Current guidelines recommend an antipseudomonal antibiotic for those at...