Dexmedetomidine or Propofol for Sedation in the Critically Ill?

July 07, 2025 00:21:54
Dexmedetomidine or Propofol for Sedation in the Critically Ill?
Critical Care Perspectives in Emergency Medicine
Dexmedetomidine or Propofol for Sedation in the Critically Ill?

Jul 07 2025 | 00:21:54

/

Show Notes

Critically ill patients receiving mechanical ventilation require analgesia and sedation.  At present, propofol remains the most widely used sedative for intubated/ventilated patients.  Recent trials have suggested that dexmedetomidine may reduce delirium and the duration of mechanical ventilation compared with other sedative medications.  In fact, recent SCCM guidelines suggest the use of dexmedetomidine over propofol in intubated patients.  In this podcast, we discuss a recent randomized trial that compared the effectiveness and safety of a dexmedetomidine-based sedation strategy with a propofol-based sedation strategy in mechanically ventilated critically ill patients.

Other Episodes

Episode 0

February 05, 2019 00:30:53
Episode Cover

ED Sepsis Screening - Is qSOFA Really Better?

As EDs across the country strive to meet sepsis benchmark metrics, many have implemented a variety of screening tools. With the publication of Sepsis-3,...

Listen

Episode 0

August 12, 2019 00:28:42
Episode Cover

Resuscitating The Critically Ill Geriatric Patient

The World’s population is aging. By 2030, 20 percent of the US population will be over the age of 65 years.  Older patients have...

Listen

Episode 0

September 17, 2019 00:19:53
Episode Cover

Do ED-Based ICUs Make a Difference?

Over the past decade, the annual hours of critical care delivered in US emergency departments has sharply risen. Undoubtedly, many critically ill patients remain...

Listen