Should We Add Fludrocortisone to Hydrocortisone for Septic Shock?

April 28, 2023 00:27:21
Should We Add Fludrocortisone to Hydrocortisone for Septic Shock?
Critical Care Perspectives in Emergency Medicine
Should We Add Fludrocortisone to Hydrocortisone for Septic Shock?

Apr 28 2023 | 00:27:21

/

Show Notes

The use of steroids in patients with sepsis and septic shock has been controversial for decades. At present, the Surviving Sepsis Campaign recommends the administration of corticosteroids to patients with persistent shock despite fluid and vasopressor administration. In recent years, several trials have evaluated the addition of fludrocortisone, a potent mineralocorticoid, to hydrocortisone in septic shock. In this podcast, we review the latest study that evaluated the combination of hydrocortisone and fludrocortisone in patients with septic shock.  Should we administer this medication with hydrocortisone for our patients with septic shock?

Other Episodes

Episode

October 15, 2025 00:34:24
Episode Cover

Critical Issues in ED Intubation

Emergency physicians intubate critically ill patients daily.  Unfortunately, up to 17% of ED intubations can be complicated by peri-intubation hypoxemia, hypotension, and cardiac arrest....

Listen

Episode 0

May 25, 2017 00:21:05
Episode Cover

Euglycemic DKA

We discuss the case of a young patient presenting with euglycemic DKA.  Say what?  How common is this entity and what is the impact...

Listen

Episode 0

April 15, 2018 00:28:52
Episode Cover

Acute Aortic Syndromes

Acute aortic syndromes such as aortic dissection are incredibly stressful and challenging to manage.  In this episode, we tackle the difficult management pearls and...

Listen