Timely and appropriate administration of empiric broad-spectrum antibiotics for adult patients with sepsis is critical. Current guidelines recommend an antipseudomonal antibiotic for those at risk of a resistant gram-negative organism. The two most common antipseudomonal antibiotics prescribed in this setting are cefepime and piperacillin-tazobactam. In recent years, observational studies have reported an association with cefepime and neurotoxicity, whereas piperacillin-tazobactam has been associated with AKI especially when given with vancomycin. In this podcast, we discuss the recently published ACORN Trial, a randomized trial that evaluated cefepime and piperacillin-tazobactam for adult patients with suspected infection.
To say that 2020 has been a challenging year would be a gross understatement. The courage and determination that all healthcare providers have shown...
Emergency medicine, critical care, and acute care providers evaluate, resuscitate, and manage patients with shock on a daily basis. Despite initial efforts, a select...
The number of critically ill elderly patients continues to increase annually. In this podcast, we discuss key pearls and pitfalls in resuscitating the sick...