Timely administration of broad-spectrum antibiotics is a critical pillar in the resuscitation of patients with sepsis. B-lactam antibiotics are an important class of antibiotics commonly administered to patients with sepsis. Typically, B-lactam antibiotics are administered over 30 minutes, but optimal bactericidal activity requires the concentration of free drug to be above the MIC of the organism for 40-70% of the dosing interval. In this podcast we discuss two recent publications that compare continuous infusions of B-lactam antibiotics with intermittent effusions in patients with sepsis.
Bryan Hayes is back! In this podcast, we discuss pitfalls in the use of benzodiazpines along with current evidence on adjunctive treatments including propofol,...
A critical component to post-arrest care for the patient with ROSC following out-of-hospital cardiac arrest is early coronary angiography. Current guidelines recommend immediate cardiac...
Over 500,000 patients suffer sudden cardiac arrest each year in the United States. Though survival rates are improving, there remains significant variation in outcomes...