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What Oxygenation Strategy Should We Use for COVID-19 Patients?
Patients with COVID-19 can require supplemental oxygen for acute hypoxemic respiratory failure. While international guidelines recommend a target SpO2 between 90-96%, a safe oxygenation...
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Should We Use NIPPV for Preoxygenation for All Intubations?
Over 1 million critically ill patients are intubated each year in the US. Hypoxemia occurs in up to 20% of patients and can lead...
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Cefepime vs. Piperacillin-Tazobactam for Infection? The ACORN Trial
Timely and appropriate administration of empiric broad-spectrum antibiotics for adult patients with sepsis is critical. Current guidelines recommend an antipseudomonal antibiotic for those at...
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Are We Ventilating our OHCA Patients?
In recent years, there has been intense focus on delivering high-quality compressions during the resuscitation of patients with OHCA. In contrast, ventilation metrics in...
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Steroids in Sepsis, ARDS, and CAP - A Focused Clinical Update
Critically ill patients commonly develop a dysregulated inflammatory response. Corticosteroids are hypothesized to be beneficial due to their anti-inflammatory properties. In recent years, several...
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Should We Intubate For GCS < 8?
Acute mental status changes after the ingestion of alcohol or other substances are a common presentation to the ED. Those with severe obtundation may...